Welcome to CPHI&P-MEC China 2014 in Shanghai! Booth No.: W4E22

We new-released ketoisocaproate derivants as well as its series products.

D-Aspartic Acid, as one kind chiral compound, plays great role in medicine, food etc, especially its important application prospect in pharmaceutical intermediates as the precursor of chiral drug synthesis. Currently, resolution of enantiomer is the main production method, of course, the enzymatic resolution is the most competitive. Application in pharmaceutical area In pharmaceutical synthesis, D-Aspartic Acid is mainly used as precursors and intermediates, such as the intermediate of Aspoxicillin (the first amino acid type penicillin in clinical use). At the same time, D-Aspartic Acid can be used in synthetizing D - Aspartate - Beta – Hydroxylamine(DAH), DAH DAH is a drug of virus infection, especially has resistant for some retroviruses and can be applied to treat AIDS, tumours etc. D-Aspartic acid joins to synthetize some antibiotic side chain, as the side chain of Beta-Lactam, it can improve the ant-bacter activity of antibiotic.The goods also can be used in synthesis of N-Methyl-D-Aspartate(NMDA, an important amino acid derivants, is the excitatory neurotransmitter L - glutamic acid homologue for mammalian central nervous system). The main route for NMDA is as below: D-Aspartic acid—(esterification) —D- Aspartic acid methyl ester hydrochloride—(DMF solvent, methyl iodide) —N-Methyl-D-Aspartic Acid Dimethyl Ester—(Base) —NMDA Application in food area D-Aspartic acid's acyl derivative has the function of resisting botulinus toxin, like myristica fragrans, D-Aspartic acid can replace sodium nitrite as a food preservative. In recent years, people gradually find and develop the application of D-Aspartic acid to enhance body function and immunity. In European and American countries, D-Aspartic acid has huge market prospect in health products. Now, we mainly adopt enzymatic resolution to product D-Aspartic acid, the commonly enzymes includes L-Asp-α- decarboxylase, L-Asp-β- Decarboxylase and Aspartase. The most mature method is using L-Asp-α- Decarboxylase to split. The enzyme can efficiently removal beta carboxyl generation L–Alanine from L-Aspartate that exists in DL-Aspartic acid, at the same time, it will have no effect on D-Aspartic acid, Thus D - aspartic acid was isolated. Zhangjiagang Specom Biochemical Co.,Ltd has gone on continued volume-produced through strain screening, optimization of technical condition, cutting cost, we can get the finished goods whose optical purity can be near 100%. As the main supplier of D-Aspartic acid, our goods primarily sell to Western, South America, Japan, Korea, India (D-Serine/ L-Serine/ L-Methionine/ L-Tryptophan/ L-Glutamine/ L-Arginine/ L-Cysteine/ N-Acetyl-L-Methionine, N-Acetyl-L-Cysteine—www.spbiochem.com)

In 2013, our company ceremoniously launches BCAA series products (including Instant BCAA)

Our factory in northern Jiangsu new-built in 2010 will be put into production this year as a pharmaceutical enterprises with the high-standard, high-baseline, please stay tuned!

In 2013, we will launch some new products: D-Arginine etc special amino acids. Welcome your enquiry!

Welcome to CPHI&P-MEC China 2013 in Shanghai! Booth No.: E6F42

Amino acid compound salt is different from traditional amino acid derivantes, It is not a simple mixture of two kinds amino acids. It is a new crystal product formed by one amino acid molecules and another (or a carboxylic acid molecule) through the form of ionic bonding. It not only has the biological action of two amino acids, but also reinforces mutually each other. At the same time, it has the better physicochemical properties than the single one. Therefore, in medicine, health-care products and cosmetics fields, it has wider application. Our company (Zhangjiagang Specom Biochemical Co., Ltd, http://www.spbiochem.com/) actively organizeed R&D capabilities, in succession developed L-Lysine L-Aspartat, L-Lysine L-Glutamate Dihydrate, L-Arginine-L-Pyroglutamate, L-Arginine L- Asparate, L-Ornithine L-Asparate, L- Arginine a-Ketoglutarate etc to meet the growing needs of the market and expand the amino acids downstream products.     Medicine Health-care products cosmetics L-Lysine L-Glutamate Dihydrate Effective resisting the formation of blood sickle cell; Can treat the metabolic disorders of children; can be used as anti ulcer agents, forming the protective film, promoting ulcer healing. For the smell is less than lysine hydrochloride, it replaces lysine salt in the high-grade food and beverages. Also used in high-grade wine, soft drinks, high-grade bread, high-grade starch products. Emulsifying, deodorization, antifreeze, low chemical oxygen consumption, non-toxic, non-stimulating, promote blood circulation. L-Lysine L-Aspartat Anti fatigue, preventing muscle atrophy Food nutrition fortifier, into the national hygienic standards for uses of food additive (GB14880-94); can remove the flavor of fish, meat, eggs, milk. Inhibiting the overmuch lactic acid secreted by scalp glands, which can protect the hair L-Arginine-L-Pyroglutamate  Enhancing immunity; treating the viral hepatitis   Making oily hair shampoo, have good effection. L-Arginine L- Asparate  Reducing the ammonia accumulation caused by exercise; treating amnesia; inhibition of arterial thrombosis   Using in cosmetics and moisturizing cream as antioxidant L-Ornithine-L-Asparate  Reducing the blood ammonia levels; treating the icteric viral hepatitis nutrition supplement of cirrhosis   L-Arginine α-Ketoglutarate Enhancing the detoxification function of liver Raw materials of health-care food   This year, amino acid compound salt is used more and more widely, the market demand is also increasing year by year. With the deepening of amino acid compound salt field, more and more functions will be developed and applied. Our company (Zhangjiagang Specom Biochemical Co.,Ltd, http://www.spbiochem.com/ ) will also keep striving and launch more and more, better and better products to rich amino acids downstream product applications. More product information, please refer to Zhangjiagang Specom Biochemical Co., Ltd- Tryptophan/Proline/Serine/Methionine/Glutamine/Arginine/Leucine/Tyrosine URL: http://www.spbiochem.com

D/DL/L-Threonine is a kind of important, organic, chiral source. It's mainly used in chiral drug, chiral additive, chiral adjuvant etc, also widely used in pharmaceutical industry. As an optically active organic acid, it has the irreplaceable effect in the asymmetric synthesis process of some chiral compounds. Currently, it's primarily used as a protective agent in the producing of new cephalosporin antibiotic, alkamine and polypeptide. Generally, D-Threonine comes from chiral resolution of DL-Threonine. However, our DL-Threonine production has several steps: complexation of Glycine and cupric sulfate--aldol condensation with acetaldehyde in the condition of decompression and catalysis--copper removal through ammonium ion exchange—concentration--ethanol extraction. Our Specom does the best to get higher product yield by continuous technical innovation, optimizing reaction conditions and handling method. 　　Our company (Zhangjiagang Specom Biochemical Co.,Ltd, http://www.spbiochem.com, supplying Tryptophan/ Methionine/ Serine/ Proline/ Glutamine/ Leucine/ Arginine Hcl/ Tyrosine) makes use of price superiority(the superiority of DL-Threonine cost ), researches and optimizes technological chain of chiral resolution, continuously improves the yield and assay of D-Threonine, thus we keep the competitive edge in domestic and oversea market. Presently we (Zhangjiagang Specom Biochemical Co.,Ltd---http://www.spbiochem.com---L-Tryptophan| L-Methionine/ N-Acetyl-DL/ L-Methionine/ L-Arginine/ L-Leucine/ L-Trosine/ L-Proline/ L-Glutamine)are the main supplier of D-Threonine in Japan and Korea. Of course, we are also the domestic unique supplier who actually produces the goods. The capacity/month is about 100kgs steadily The essay links to Zhangjiagang Specom Biochemical Co., Ltd.—http://www.spbiochem.com

Ardently celebrate a new website of Zhangjiagang Specom Biochemical Co., LTD official opening!